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This is a general overview. For more in-depth information, see our health professional fact sheet.. What is vitamin B12 and what does it do? Vitamin B12 is a nutrient that helps keep your body's blood and nerve cells healthy and helps make DNA, the genetic material in all of your cells. Vitamin B12 also helps prevent megaloblastic anemia, a blood condition that makes people tired and weak.. Absorption rates improve with supplementation; therefore, patients older than 50 years and vegans or strict vegetarians should consume foods fortified with vitamin B12 or take vitamin B12 supplements.

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Vitamin B12 functions as an essential coenzyme in humans. The absorption of this molecule and its subsequent distribution in the body is mediated by a complex set of carrier proteins, receptors.. Vitamin B12 absorption. Vitamin B12 absorption is a highly complex process that often becomes less efficient with age, and involves the stomach, pancreas and small intestine.. This is a clinical perspective on the approaches to treat and prevent vitamin B12 deficiency. [Google Scholar] 11.