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Sertraline, which goes by the brand name Zoloft, is a common antidepressant. This article provides an overview of sertraline, including its uses, dosages, side effects, and interactions.. Sertraline is an effective antidepressant with less potential for drowsiness than other antidepressants. Headaches, nausea, diarrhea, weight loss, insomnia, tremors, and sexual dysfunction are the most common side effects reported. 5. Tips. May be taken with or without food; however, this needs to be consistent.
